EC |
3.5.1.29 |
Accepted name: |
2-(acetamidomethylene)succinate hydrolase |
Reaction: |
2-(acetamidomethylene)succinate + 2 H2O = acetate + succinate semialdehyde + NH3 + CO2 |
Other name(s): |
α-(N-acetylaminomethylene)succinic acid hydrolase |
Systematic name: |
2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating) |
Comments: |
Involved in the degradation of pyridoxin in Pseudomonas. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37289-09-1 |
References: |
1. |
Huynh, M.S. and Snell, E.E. Enzymes of vitamin B6 degradation. Purification and properties of two N-acetylamidohydrolases. J. Biol. Chem. 260 (1985) 2379–2383. [PMID: 3972793] |
2. |
Nyns, E.J., Zach, D. and Snell, E.E. The bacterial oxidation of vitamin B6. 8. Enzymatic breakdown of α-(N-acetylaminomethylene) succinic acid. J. Biol. Chem. 244 (1969) 2601–2605. [PMID: 5769993] |
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[EC 3.5.1.29 created 1972] |
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