| EC |
3.5.1.44 |
| Accepted name: |
protein-glutamine glutaminase |
| Reaction: |
protein L-glutamine + H2O = protein L-glutamate + NH3 |
| Other name(s): |
peptidoglutaminase II; glutaminyl-peptide glutaminase; destabilase; peptidylglutaminase II |
| Systematic name: |
protein-L-glutamine amidohydrolase |
| Comments: |
Specific for the hydrolysis of the γ-amide of glutamine substituted at the carboxyl position or both the α-amino and carboxyl positions, e.g., L-glutaminylglycine and L-phenylalanyl-L-glutaminylglycine. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 62213-11-0 |
| References: |
| 1. |
Kikuchi, M., Hayashida, H., Nakano, E. and Sakaguchi, K. Peptidoglutaminase. Enzymes for selective deamidation of γ-amide of peptide-bound glutamine. Biochemistry 10 (1971) 1222–1229. [PMID: 4928623] |
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| [EC 3.5.1.44 created 1976, modified 1983] |
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