ExplorEnz: EC 3.5.3.18

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3.5.3.18

Accepted name:

dimethylargininase

Reaction:

N^ω,N^ω′-dimethyl-L-arginine + H₂O = dimethylamine + L-citrulline

Other name(s):

dimethylarginine dimethylaminohydrolase; N^G,N^G-dimethylarginine dimethylaminohydrolase; N^G,N^G-dimethyl-L-arginine dimethylamidohydrolase; ω,ω’-di-N-methyl-L-arginine dimethylamidohydrolase; N^ω,N^ω′-methyl-L-arginine dimethylamidohydrolase (incorrect)

Systematic name:

N^ω,N^ω′-dimethyl-L-arginine dimethylamidohydrolase

Comments:

Also acts on N^ω-methyl-L-arginine.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 123644-75-7

References:

1.	Ogawa, T., Kimoto, M. and Sasaoka, K. Purification and properties of a new enzyme, N^G,N^G-dimethylarginine dimethylaminohydrolase, from rat kidney. J. Biol. Chem. 264 (1989) 10205–10209. [PMID: 2722865]

[EC 3.5.3.18 created 1992]