| EC |
3.5.4.11 |
| Accepted name: |
pterin deaminase |
| Reaction: |
a 2-amino-4-hydroxypteridine + H2O = a 2,4-dihydroxypteridine + NH3 |
| Other name(s): |
acrasinase |
| Systematic name: |
2-amino-4-hydroxypteridine aminohydrolase |
| Comments: |
The animal enzyme is specific for pterin, isoxanthopterin and tetrahydropterin. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 9025-04-1 |
| References: |
| 1. |
Levenberg, B. and Hayaishi, O. A bacterial pterin deaminase. J. Biol. Chem. 234 (1959) 955–961. [PMID: 13654299] |
| 2. |
Rembold, H. and Simmersbach, F. Catabolism of pteridine cofactors. II. A specific pterin deaminase in rat liver. Biochim. Biophys. Acta 184 (1969) 589–596. [DOI] [PMID: 5821022] |
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| [EC 3.5.4.11 created 1965] |
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