| EC |
3.5.4.12 |
| Accepted name: |
dCMP deaminase |
| Reaction: |
dCMP + H2O = dUMP + NH3 |
| Other name(s): |
deoxycytidylate deaminase; deoxy-CMP-deaminase; deoxycytidylate aminohydrolase; deoxycytidine monophosphate deaminase; deoxycytidine-5′-phosphate deaminase; deoxycytidine-5′-monophosphate aminohydrolase |
| Systematic name: |
dCMP aminohydrolase |
| Comments: |
Also acts on some 5-substituted dCMPs. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9026-92-0 |
| References: |
| 1. |
Scarano, E. The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5′-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5′-phosphate. J. Biol. Chem. 235 (1960) 706–713. [PMID: 14442222] |
| 2. |
Scarano, E., Bonaduce, L. and de Petrocellis, B. The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5′-phosphate deaminase from unfertilized eggs of sea urchin. J. Biol. Chem. 235 (1960) 3556–3561. [PMID: 13747062] |
| 3. |
Sergott, R.C., Debeer, L.J. and Bessman, M.J. On the regulation of a bacterial deoxycytidylate deaminase. J. Biol. Chem. 246 (1971) 7755–7758. [PMID: 5002683] |
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| [EC 3.5.4.12 created 1965] |
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