| EC |
3.5.4.22 |
| Accepted name: |
1-pyrroline-4-hydroxy-2-carboxylate deaminase |
| Reaction: |
1-pyrroline-4-hydroxy-2-carboxylate + H2O = 2,5-dioxopentanoate + NH3 |
| Other name(s): |
HPC deaminase; 1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing) |
| Systematic name: |
1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (ring-opening) |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9054-77-7 |
| References: |
| 1. |
Singh, R.M.M. and Adams, E. Enzymatic deamination of Δ1-pyrroline-4-hydroxy-2-carboxylate to 2,5-dioxovalerate (α-ketoglutaric semialdehyde). J. Biol. Chem. 240 (1965) 4344–4351. [PMID: 5845838] |
| 2. |
Singh, R.M.M. and Adams, E. Isolation and identification of 2,5-dioxovalerate, an intermediate in the bacterial oxidation of hydroxyproline. J. Biol. Chem. 240 (1965) 4352–4356. [PMID: 5845839] |
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| [EC 3.5.4.22 created 1976] |
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