| EC |
3.5.4.27 |
| Accepted name: |
methenyltetrahydromethanopterin cyclohydrolase |
| Reaction: |
5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = 5-formyl-5,6,7,8-tetrahydromethanopterin |
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For diagram of methane biosynthesis, click here |
| Glossary: |
tetrahydromethanopterin = 1-(4-{(1R)-1-[(6S,7S)-2-amino-7-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]ethylamino}phenyl)-1-deoxy-5-O-{5-O-[(1S)-1,3-dicarboxypropylphosphonato]-α-D-ribofuranosyl}-D-ribitol |
| Other name(s): |
5,10-methenyltetrahydromethanopterin cyclohydrolase; N5,N10-methenyltetrahydromethanopterin cyclohydrolase; methenyl-H4MPT cyclohydrolase; 5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing) |
| Systematic name: |
5,10-methenyltetrahydromethanopterin 10-hydrolase (ring-opening) |
| Comments: |
Methanopterin is a pterin analogue. The enzyme is involved in the formation of methane from CO2 in Methanobacterium thermoautotrophicum. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 99533-50-3 |
| References: |
| 1. |
Donnelly, M.I., Escalante-Semerena, J.C., Rinehart, K.L., Jr. and Wolfe, R.S. Methenyl-tetrahydromethanopterin cyclohydrolase in cell extracts of Methanobacterium. Arch. Biochem. Biophys. 242 (1985) 430–439. [DOI] [PMID: 4062290] |
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| [EC 3.5.4.27 created 1989] |
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