EC |
3.5.4.3 |
Accepted name: |
guanine deaminase |
Reaction: |
guanine + H2O = xanthine + NH3 |
Other name(s): |
guanase; guanine aminase; GAH |
Systematic name: |
guanine aminohydrolase |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9033-16-3 |
References: |
1. |
Hitchings, G.H. and Falco, E.A. The identification of guanine in extracts of Girella nigricans. The specificity of guanase. Proc. Natl. Acad. Sci. USA 30 (1944) 294–297. [DOI] [PMID: 16578130] |
2. |
Kalckar, H.M. Differential spectrophotometry of purine compounds by means of specific enzymes. III. Studies of the enzymes of purine metabolism. J. Biol. Chem. 167 (1947) 461–475. [PMID: 20285041] |
3. |
Rabinowitz, J.C. and Barker, H.A. Purine fermentation by Clostridium cylindrosporum. II. Purine transformations. J. Biol. Chem. 218 (1956) 161–173. [PMID: 13278325] |
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[EC 3.5.4.3 created 1961] |
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