| EC |
3.5.4.45 |
| Accepted name: |
melamine deaminase |
| Reaction: |
(1) melamine + H2O = ammeline + NH3
(2) ammeline + H2O = ammelide + NH3 |
| Glossary: |
melamine = 2,4,6-triamino-1,3,5-triazine
ammeline = 4,6-diamino-1,3,5-triazin-2-ol
ammelide = 6-amino-1,3,5-triazine-2,4-diol |
| Other name(s): |
triA (gene name) |
| Systematic name: |
melamine aminohydrolase |
| Comments: |
The enzyme, isolated from the bacterium Acidovorax citrulli, performs the deamination of melamine 15-fold faster than the deamination of ammeline. It also has activity with 2-chloro-4,6-diamino-s-triazine, but has no activity toward halo-substituted triazine ring compounds such as atrazine (cf. EC 3.8.1.8, atrazine chlorohydrolase). |
| References: |
| 1. |
Seffernick, J.L., Souza, M.L., Sadowsky, M.J. and Wackett, L.P. Melamine deaminase and atrazine chlorohydrolase: 98 percent identical but functionally different. J. Bacteriol. 183 (2001) 2405–2410. [PMID: 11274097] |
|
| [EC 3.5.4.45 created 2017] |
| |
|
| |
|