| EC |
3.5.4.46 |
| Accepted name: |
cAMP deaminase |
| Reaction: |
3′,5′-cyclic AMP + H2O = 3′,5′-cyclic IMP + NH3 |
| Other name(s): |
cyclic adenylate deaminase; CadD |
| Systematic name: |
3′,5′-cyclic AMP aminohydrolase |
| Comments: |
Requires Zn2+. The enzyme, isolated from the bacterium Leptospira interrogans, is specific for cAMP. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Goble, A.M., Feng, Y., Raushel, F.M. and Cronan, J.E. Discovery of a cAMP deaminase that quenches cyclic AMP-dependent regulation. ACS Chem. Biol. 8 (2013) 2622–2629. [DOI] [PMID: 24074367] |
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| [EC 3.5.4.46 created 2017] |
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