| EC |
3.5.5.5 |
| Accepted name: |
arylacetonitrilase |
| Reaction: |
4-chlorophenylacetonitrile + 2 H2O = 4-chlorophenylacetate + NH3 |
| Systematic name: |
arylacetonitrile aminohydrolase |
| Comments: |
Requires thiol compounds. Also hydrolyses other 4-substituted phenylacetonitriles, thien-2-ylacetonitrile, tolylacetonitriles, and, more slowly, benzyl cyanide. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 132053-06-6 |
| References: |
| 1. |
Mauger, J., Nagasawa, T. and Yamada, H. Occurrence of a novel nitrilase, arylacetonitrilase, in Alcaligenes faecalis JM3. Arch. Microbiol. 155 (1990) 1–6. |
| 2. |
Nagasawa, T., Mauger, J. and Yamada, H. A novel nitrilase, arylacetonitrilase, of Alcaligenes faecalis JM3. Purification and characterization. Eur. J. Biochem. 194 (1990) 765–772. [DOI] [PMID: 2269298] |
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| [EC 3.5.5.5 created 1992] |
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