| EC |
3.5.5.7 |
| Accepted name: |
aliphatic nitrilase |
| Reaction: |
R-CN + 2 H2O = R-COOH + NH3 |
| Systematic name: |
aliphatic nitrile aminohydrolase |
| Comments: |
Preferentially hydrolyses aliphatic nitriles, some of which are apparently not substrates for other known nitrilases (EC 3.5.5.1). Substrates include crotononitrile, acrylonitrile and glutaronitrile. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 395644-15-2 |
| References: |
| 1. |
Kobayashi, M., Yanaka, N., Nagasawa, T., Yamada, H. Primary structure of an aliphatic nitrile-degrading enzyme, aliphatic nitrilase from Rhodococcus rhodochrous K22 and expression of its gene and identification of its active site residue. Biochemistry 31 (1992) 9000–9007. [PMID: 1390687] |
| 2. |
Pace, H.C. and Brenner, C. The nitrilase superfamily: classification, structure and function. Genome Biol. 2 (2001) 0001.. [PMID: 11380987] |
|
| [EC 3.5.5.7 created 1999] |
| |
|
| |
|
Printable version