ExplorEnz: EC 3.5.5.8

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3.5.5.8

Accepted name:

thiocyanate hydrolase

Reaction:

thiocyanate + 2 H₂O = carbonyl sulfide + NH₃ + HO^-

Systematic name:

thiocyanate aminohydrolase

Comments:

The enzyme from Thiobacillus thioparus catalyses the first step in the degradation of thiocyanate.

Links to other databases:

BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 142539-65-9

References:

1.	Katayama, Y., Matsushita, Y., Kaneko, M., Kondo, M., Mizuno, T. and Nyunoya, H. Cloning of genes coding for the three subunits of thiocyanate hydrolase of Thiobacillus thioparus THI 115 and their evolutionary relationships to nitrile hydratase. J. Bacteriol. 180 (1998) 2583–2589. [PMID: 9573140]
2.	Katayama, Y., Narahara, Y., Inoue, Y., Amano, F., Kanagawa, T. and Kuraishi, H. A thiocyanate hydrolase of Thiobacillus thioparus. J. Biol. Chem. 267 (1992) 9170–9175. [PMID: 1577754]

[EC 3.5.5.8 created 2000]