The Enzyme Database

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Accepted name: 2-nitroimidazole nitrohydrolase
Reaction: 2-nitroimidazole + H2O = imidazol-2-one + nitrite
Other name(s): NnhA; 2NI nitrohydrolase; 2NI denitrase
Systematic name: 2-nitroimidazole nitrohydrolase
Comments: The enzyme catalyses the initial step in the biodegradation of 2-nitroimidazole by the soil bacterium Mycobacterium sp. JS330
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Qu, Y. and Spain, J.C. Catabolic pathway for 2-nitroimidazole involves a novel nitrohydrolase that also confers drug resistance. Environ. Microbiol. 13 (2011) 1010–1017. [DOI] [PMID: 21244596]
[EC created 2012]

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