| EC |
3.5.99.9 |
| Accepted name: |
2-nitroimidazole nitrohydrolase |
| Reaction: |
2-nitroimidazole + H2O = imidazol-2-one + nitrite |
| Other name(s): |
NnhA; 2NI nitrohydrolase; 2NI denitrase |
| Systematic name: |
2-nitroimidazole nitrohydrolase |
| Comments: |
The enzyme catalyses the initial step in the biodegradation of 2-nitroimidazole by the soil bacterium Mycobacterium sp. JS330 |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Qu, Y. and Spain, J.C. Catabolic pathway for 2-nitroimidazole involves a novel nitrohydrolase that also confers drug resistance. Environ. Microbiol. 13 (2011) 1010–1017. [DOI] [PMID: 21244596] |
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| [EC 3.5.99.9 created 2012] |
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