The Enzyme Database

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Accepted name: guanosine-5′-triphosphate,3′-diphosphate phosphatase
Reaction: guanosine 5′-triphosphate 3′-diphosphate + H2O = guanosine 3′,5′-bis(diphosphate) + phosphate
Other name(s): pppGpp 5′-phosphohydrolase; guanosine 5′-triphosphate-3′-diphosphate 5′-phosphohydrolase; guanosine pentaphosphatase; guanosine pentaphosphate phosphatase; guanosine 5′-triphosphate 3′-diphosphate 5′-phosphatase; guanosine pentaphosphate phosphohydrolase
Systematic name: guanosine-5′-triphosphate-3′-diphosphate 5′-phosphohydrolase
Comments: Also hydrolyses other guanosine 5′-triphosphate derivatives with at least one unsubstituted phosphate group on the 3′-position, but not GTP, ATP or adenosine 5′-triphosphate 3′-diphosphate.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 85130-44-5
1.  Hara, A. and Sy, J. Guanosine 5′-triphosphate, 3′-diphosphate 5′-phosphohydrolase. Purification and substrate specificity. J. Biol. Chem. 258 (1983) 1678–1683. [PMID: 6130093]
[EC created 1986, modified 2010]

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