| EC |
4.1.1.123 |
| Accepted name: |
phenyl-phosphate phosphatase/carboxylase |
| Reaction: |
4-hydroxybenzoate + phosphate = phenyl phosphate + CO2 + H2O |
| Other name(s): |
phenyl phosphate carboxylase |
| Systematic name: |
4-hydroxybenzoate carboxy-lyase (phenyl phosphate-forming) |
| Comments: |
The enzyme, characterized from the bacterium Thauera aromatica, participates in an anaerobic phenol degradation pathway. It catalyses the para dephosphorylation and carboxylation of phenylphosphate to 4-hydroxybenzoate. The enzyme from Thauera aromatica consists of four different subunits and requires K+ and a divalent metal cation (Mg2+ or Mn2+) for activity. It is strongly inhibited by oxygen. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Schuhle, K. and Fuchs, G. Phenylphosphate carboxylase: a new C-C lyase involved in anaerobic phenol metabolism in Thauera aromatica. J. Bacteriol. 186 (2004) 4556–4567. [DOI] [PMID: 15231788] |
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| [EC 4.1.1.123 created 2022] |
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