EC |
4.1.1.43 |
Accepted name: |
phenylpyruvate decarboxylase |
Reaction: |
phenylpyruvate = phenylacetaldehyde + CO2 |
Glossary: |
phenylpyruvate = 3-phenyl-2-oxopropanoate |
Other name(s): |
phenylpyruvate carboxy-lyase; phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming) |
Systematic name: |
3-phenyl-2-oxopropanoate carboxy-lyase (phenylacetaldehyde-forming) |
Comments: |
The enzyme from the bacterium Azospirillum brasilense also acts on some other substrates, including (indol-3-yl)pyruvate, with much lower efficiency. However, it only possesses classical Michaelis-Menten kinetics with phenylpyruvate. Aliphatic 2-oxo acids longer that 2-oxohexanoate are not substrates. cf. EC 4.1.1.74, indolepyruvate decarboxylase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37289-45-5 |
References: |
1. |
Asakawa, T., Wada, H. and Yamano, T. Enzymatic conversion of phenylpyruvate to phenylacetate. Biochim. Biophys. Acta 170 (1968) 375–391. [DOI] [PMID: 4303395] |
2. |
Spaepen, S., Versees, W., Gocke, D., Pohl, M., Steyaert, J. and Vanderleyden, J. Characterization of phenylpyruvate decarboxylase, involved in auxin production of Azospirillum brasilense. J. Bacteriol. 189 (2007) 7626–7633. [PMID: 17766418] |
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[EC 4.1.1.43 created 1972] |
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