The Enzyme Database

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Accepted name: hydroxymandelonitrile lyase
Reaction: (S)-4-hydroxymandelonitrile = cyanide + 4-hydroxybenzaldehyde
Other name(s): hydroxynitrile lyase; oxynitrilase; Sorghum hydroxynitrile lyase; (S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase
Systematic name: (S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming)
Comments: Does not accept aliphatic hydroxynitriles, unlike EC (mandelonitrile lyase), EC [aliphatic (R)-hydroxynitrile lyase] and EC [(S)-hydroxynitrile ketone-lyase (cyanide forming)].
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9075-38-1
1.  Bové, C. and Conn, E.E. Metabolism of aromatic compounds in higher plants. II. Purification and properties of the oxynitrilase of Sorghum vulgare. J. Biol. Chem. 236 (1961) 207–210.
2.  Seely, M.K., Criddle, R.S. and Conn, E.E. The metabolism of aromatic compounds in higher plants. 8. On the requirement of hydroxynitrile lyase for flavin. J. Biol. Chem. 241 (1966) 4457–4462. [PMID: 5922969]
[EC created 1965, modified 1999]

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