| EC |
4.2.1.123 |
| Accepted name: |
tetrahymanol synthase |
| Reaction: |
tetrahymanol = squalene + H2O |
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For diagram of hopene and tetrahymanol biosynthesis, click here |
| Glossary: |
tetrahymanol = gammaceran-3β-ol |
| Systematic name: |
squalene hydro-lyase (tetrahymanol-forming) |
| Comments: |
The reaction occurs in the reverse direction. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Saar, J., Kader, J.C., Poralla, K. and Ourisson, G. Purification and some properties of the squalene-tetrahymanol cyclase from Tetrahymena thermophila. Biochim. Biophys. Acta 1075 (1991) 93–101. [DOI] [PMID: 1892870] |
| 2. |
Giner, J.L., Rocchetti, S., Neunlist, S., Rohmer, M. and Arigoni, D. Detection of 1,2-hydride shifts in the formation of euph-7-ene by the squalene-tetrahymanol cyclase of Tetrahymena pyriformis. Chem. Commun. (Camb.) (2005) 3089–3091. [DOI] [PMID: 15959594] |
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| [EC 4.2.1.123 created 2011] |
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