| EC |
4.2.1.125 |
| Accepted name: |
dammarenediol II synthase |
| Reaction: |
dammarenediol II = (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O |
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For diagram of dammarenediol II and tirucalla-7,24-dien-3β-ol biosynthesis, click here |
| Other name(s): |
dammarenediol synthase; 2,3-oxidosqualene (20S)-dammarenediol cyclase; DDS; (S)-squalene-2,3-epoxide hydro-lyase (dammarenediol-II forming) |
| Systematic name: |
(3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (dammarenediol-II-forming) |
| Comments: |
The reaction occurs in the reverse direction. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 189354-84-5 |
| References: |
| 1. |
Tansakul, P., Shibuya, M., Kushiro, T. and Ebizuka, Y. Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng. FEBS Lett. 580 (2006) 5143–5149. [DOI] [PMID: 16962103] |
| 2. |
Han, J.Y., Kwon, Y.S., Yang, D.C., Jung, Y.R. and Choi, Y.E. Expression and RNA interference-induced silencing of the dammarenediol synthase gene in Panax ginseng. Plant Cell Physiol. 47 (2006) 1653–1662. [DOI] [PMID: 17088293] |
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| [EC 4.2.1.125 created 2011] |
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