EC |
4.2.1.133 |
Accepted name: |
copal-8-ol diphosphate hydratase |
Reaction: |
(13E)-8α-hydroxylabd-13-en-15-yl diphosphate = geranylgeranyl diphosphate + H2O |
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For diagram of hydroxylabdenyl diphosphate derived diterpenoids, click here |
Glossary: |
(13E)-8α-hydroxylabd-13-en-15-yl diphosphate = 8-hydroxycopalyl diphosphate |
Other name(s): |
CcCLS |
Systematic name: |
geranylgeranyl-diphosphate hydro-lyase [(13E)-8α-hydroxylabd-13-en-15-yl diphosphate-forming] |
Comments: |
Requires Mg2+. The enzyme was characterized from the plant Cistus creticus subsp. creticus. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Falara, V., Pichersky, E. and Kanellis, A.K. A copal-8-ol diphosphate synthase from the angiosperm Cistus creticus subsp. creticus is a putative key enzyme for the formation of pharmacologically active, oxygen-containing labdane-type diterpenes. Plant Physiol. 154 (2010) 301–310. [DOI] [PMID: 20595348] |
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[EC 4.2.1.133 created 2012] |
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