| EC |
4.2.1.17 |
| Accepted name: |
enoyl-CoA hydratase |
| Reaction: |
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O |
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For diagram of aerobic phenylacetate catabolism, click here |
| Other name(s): |
enoyl hydrase; unsaturated acyl-CoA hydratase; β-hydroxyacyl-CoA dehydrase; β-hydroxyacid dehydrase; acyl coenzyme A hydrase; crotonase; crotonyl hydrase; 2-octenoyl coenzyme A hydrase; enoyl coenzyme A hydratase; 2-enoyl-CoA hydratase; short-chain enoyl-CoA hydratase; ECH; trans-2-enoyl-CoA hydratase; enoyl coenzyme A hydrase (D); enoyl coenzyme A hydrase (L); short chain enoyl coenzyme A hydratase; D-3-hydroxyacyl-CoA dehydratase; enol-CoA hydratase |
| Systematic name: |
(3S)-3-hydroxyacyl-CoA hydro-lyase |
| Comments: |
Acts in the reverse direction. With cis-compounds, yields (3R)-3-hydroxyacyl-CoA. cf. EC 4.2.1.74 long-chain-enoyl-CoA hydratase. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9027-13-8 |
| References: |
| 1. |
Moskowitz, G.J. and Merrick, J.M. Metabolism of poly-β-hydroxybutyrate. II. Enzymatic synthesis of D-(-)-β-hydroxybutyryl coenzyme A by an enoyl hydrase from Rhodospirillum rubrum. Biochemistry 8 (1969) 2748–2755. [PMID: 5808333] |
| 2. |
Stern, J.R. Thioltranscrotylase and β-hydroxybutyryl CoA racemase activities of crystalline crotonase. Biochim. Biophys. Acta 26 (1957) 641–643. [DOI] [PMID: 13499425] |
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| [EC 4.2.1.17 created 1961] |
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