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Your query returned 1 entry. 
Printable version
| EC | 4.2.1.170 | ||
| Accepted name: | 2-(ω-methylthio)alkylmalate dehydratase | ||
| Reaction: | (1) a 2-[(ω-methylsulfanyl)alkyl]malate = a 2-[(ω-methylsulfanyl)alkyl]maleate + H2O (2) a 3-[(ω-methylsulfanyl)alkyl]malate = a 2-[(ω-methylsulfanyl)alkyl]maleate + H2O |
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| For diagram of L-Homomethionine biosynthesis, click here | |||
| Other name(s): | IPMI (gene name); 2-[(ω-methylthio)alkyl]malate hydro-lyase (2-[(ω-methylthio)alkyl]maleate-forming) | ||
| Systematic name: | 2-[(ω-methylsulfanyl)alkyl]malate hydro-lyase (2-[(ω-methylsulfanyl)alkyl]maleate-forming) | ||
| Comments: | The enzyme, characterized from the plant Arabidopsis thaliana, is involved in the L-methionine side-chain elongation pathway, forming substrates for the biosynthesis of aliphatic glucosinolates. By catalysing a dehydration of a 2-[(ω-methylsulfanyl)alkyl]maleate, followed by a hydration at a different position, the enzyme achieves the isomerization of its substrates. The enzyme is a heterodimer comprising a large and a small subunits. The large subunit can also bind to an alternative small subunit, forming EC 4.2.1.33, 3-isopropylmalate dehydratase, which participates in L-leucine biosynthesis. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
| References: |
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