The Enzyme Database

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EC 4.2.1.174     
Accepted name: peregrinol diphosphate synthase
Reaction: peregrinol diphosphate = geranylgeranyl diphosphate + H2O
For diagram of hydroxylabdenyl diphosphate derived diterpenoids, click here
Glossary: peregrinol diphosphate = (13E)-9-hydroxy-8α-labda-13-en-15-yl diphosphate
Other name(s): MvCPS1
Systematic name: geranylgeranyl-diphosphate hydro-lyase (peregrinol-diphosphate-forming)
Comments: Isolated from the plant Marrubium vulgare (white horehound). Involved in marrubiin biosynthesis.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Zerbe, P., Chiang, A., Dullat, H., O'Neil-Johnson, M., Starks, C., Hamberger, B. and Bohlmann, J. Diterpene synthases of the biosynthetic system of medicinally active diterpenoids in Marrubium vulgare. Plant J. 79 (2014) 914–927. [DOI] [PMID: 24990389]
[EC 4.2.1.174 created 2017]
 
 


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