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Your query returned 1 entry. 
Printable version
| EC | 4.2.1.3 | ||||||
| Accepted name: | aconitate hydratase | ||||||
| Reaction: | citrate = isocitrate (overall reaction) (1a) citrate = cis-aconitate + H2O (1b) cis-aconitate + H2O = isocitrate |
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| For diagram of the citric acid cycle, click here and for diagram of the glyoxylate cycle, click here | |||||||
| Glossary: | isocitrate = (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate (previously known as threo-Ds-isocitrate) cis-aconitate = (Z)-prop-1-ene-1,2,3-tricarboxylate |
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| Other name(s): | cis-aconitase; aconitase; AcnB; 2-methylaconitate hydratase; citrate(isocitrate) hydro-lyase | ||||||
| Systematic name: | citrate(isocitrate) hydro-lyase (cis-aconitate-forming) | ||||||
| Comments: | Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate. The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate. cis-Aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-tricarboxylate. An iron-sulfur protein, containing a [4Fe-4S] cluster to which the substrate binds. | ||||||
| Links to other databases: | BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9024-25-3 | ||||||
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