| EC |
4.2.1.39 |
| Accepted name: |
gluconate dehydratase |
| Reaction: |
D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O |
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For diagram of the Entner-Doudoroff pathway, click here |
| Other name(s): |
D-gluconate dehydratase; D-gluconate hydro-lyase |
| Systematic name: |
D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming) |
| Comments: |
The enzyme shows no activity with D-galactonate [2]. cf. EC 4.2.1.140, gluconate/galactonate dehydratase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37290-75-8 |
| References: |
| 1. |
Andreesen, J.R. and Gottschalk, G. The occurrence of a modified Entner-Doudoroff pathway in Clostridium aceticum. Arch. Mikrobiol. 69 (1969) 160–170. [PMID: 5383859] |
| 2. |
Bender, R. and Gottschalk, G. Purification and properties of D-gluconate dehydratase from Clostridium pasteurianum. Eur. J. Biochem. 40 (1973) 309–321. [DOI] [PMID: 4772682] |
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| [EC 4.2.1.39 created 1972] |
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