| EC |
4.2.1.88 |
| Accepted name: |
synephrine dehydratase |
| Reaction: |
(R)-synephrine = (4-hydroxyphenyl)acetaldehyde + methylamine |
| Glossary: |
(R)-synephrine = D-(-)-synephrine = 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol |
| Other name(s): |
syringinase |
| Systematic name: |
(R)-synephrine hydro-lyase (methylamine-forming) |
| Comments: |
Removal of H2O from (R)-synephrine produces a 2,3-enamine, which hydrolyses to the products shown in the reaction above. The enzyme from Arthrobacter synephrinum is highly specific [1]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 104118-54-9 |
| References: |
| 1. |
Veeraswamy, M., Devi, N.A., Krishnan Kutty, R. and Subba Rao, P.V. Conversion of (±) synephrine into p-hydroxyphenylacetaldehyde by Arthrobacter synephrinum. A novel enzymic reaction. Biochem. J. 159 (1976) 807–809. [PMID: 1008837] |
| 2. |
Manne, V., Kutty, K.R. and Pillarisetti, S.R. Purification and properties of synephrinase from Arthrobacter synephrinum. Arch. Biochem. Biophys. 248 (1986) 324–334. [DOI] [PMID: 3729420] |
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| [EC 4.2.1.88 created 1989, modified 2012] |
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