| EC |
4.2.1.91 |
| Accepted name: |
arogenate dehydratase |
| Reaction: |
L-arogenate = L-phenylalanine + H2O + CO2 |
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For diagram of phenylalanine and tyrosine biosynthesis, click here |
| Other name(s): |
carboxycyclohexadienyl dehydratase; L-arogenate hydro-lyase (decarboxylating) |
| Systematic name: |
L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming) |
| Comments: |
Also acts on prephenate and D-prephenyllactate. cf. EC 4.2.1.51, prephenate dehydratase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 76600-70-9 |
| References: |
| 1. |
Fischer, R. and Jensen, R. Arogenate dehydratase. Methods Enzymol. 142 (1987) 495–502. [PMID: 3600377] |
| 2. |
Zamir, L.O., Tiberio, R., Devor, K.A., Sauriol, F., Ahmad, S. and Jensen, R.A. Structure of D-prephenyllactate. A carboxycyclohexadienyl metabolite from Neurospora crassa. J. Biol. Chem. 263 (1988) 17284–17290. [PMID: 2972718] |
| 3. |
Siehl, D.L. and Conn, E.E. Kinetic and regulatory properties of arogenate dehydratase in seedlings of Sorghum bicolor (L.) Moench. Arch. Biochem. Biophys. 260 (1988) 822–829. [DOI] [PMID: 3124763] |
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| [EC 4.2.1.91 created 1992, modified 2005] |
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