| EC |
4.2.2.28 |
| Accepted name: |
α-L-rhamnosyl-(1→4)-D-glucuronate lyase |
| Reaction: |
α-L-rhamnosyl-(1→4)-D-glucuronate = L-rhamnopyranose + 4-deoxy-L-threo-hex-4-enopyranuronate |
| Other name(s): |
L-rhamnose-α-1,4-D-glucuronate lyase; FoRham (gene name) |
| Systematic name: |
α-L-rhamnosyl-(1→4)-D-glucuronate lyase |
| Comments: |
The enzyme, characterized from the phytopathogenic fungus Fusarium oxysporum, removes the rhamnosyl residue from α-L-rhamnosyl-(1→4)-D-glucuronate or (with lower activity) from oligosaccharides that contain this motif at the non-reducing end, leaving an unsaturated glucuronate residue. Among its natural substrates is the type II arabinogalactan component of gum arabic. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Kondo, T., Kichijo, M., Maruta, A., Nakaya, M., Takenaka, S., Arakawa, T., Fushinobu, S. and Sakamoto, T. Structural and functional analysis of gum arabic L-rhamnose-α-1,4-D-glucuronate lyase establishes a novel polysaccharide lyase family. J. Biol. Chem. 297:101001 (2021). [DOI] [PMID: 34303708] |
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| [EC 4.2.2.28 created 2022, modified 2024] |
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