| EC |
4.2.2.7 |
| Accepted name: |
heparin lyase |
| Reaction: |
Eliminative cleavage of polysaccharides containing (1→4)-linked D-glucuronate or L-iduronate residues and (1→4)-α-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-α-D-gluc-4-enuronosyl groups at their non-reducing ends |
| Other name(s): |
heparin eliminase; heparinase |
| Systematic name: |
heparin lyase |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9025-39-2 |
| References: |
| 1. |
Hovingh, P. and Linker, A. The enzymatic degradation of heparin and heparitin sulfate. 3. Purification of a heparitinase and a heparinase from flavobacteria. J. Biol. Chem. 245 (1970) 6170–6175. [PMID: 5484472] |
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| [EC 4.2.2.7 created 1972] |
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