| EC |
4.2.3.10 |
| Accepted name: |
(-)-endo-fenchol synthase |
| Reaction: |
geranyl diphosphate + H2O = (-)-endo-fenchol + diphosphate |
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For diagram of monoterpenoid biosynthesis, click here |
| Other name(s): |
(-)-endo-fenchol cyclase; geranyl pyrophosphate:(-)-endo-fenchol cyclase |
| Systematic name: |
geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming] |
| Comments: |
(3R)-Linalyl diphosphate is an intermediate in the reaction |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 117758-41-5 |
| References: |
| 1. |
Croteau, R., Miyazaki, J.H. and Wheeler, C.J. Monoterpene biosynthesis: mechanistic evaluation of the geranyl pyrophosphate:(-)-endo-fenchol cyclase from fennel (Foeniculum vulgare). Arch. Biochem. Biophys. 269 (1989) 507–516. [DOI] [PMID: 2919880] |
| 2. |
Croteau, R., Satterwhite, D.M., Wheeler, C.J. and Felton, N.M. Biosynthesis of monoterpenes. Stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (-)-endo-fenchol. J. Biol. Chem. 263 (1988) 15449–15453. [PMID: 3170591] |
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| [EC 4.2.3.10 created 1992 as EC 4.6.1.8, transferred 2000 to EC 4.2.3.10] |
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