| EC |
4.2.3.103 |
| Accepted name: |
ent-isokaurene synthase |
| Reaction: |
ent-copalyl diphosphate = ent-isokaurene + diphosphate |
|
For diagram of biosynthesis of diterpenoids from ent-copalyl diphosphate, click here and for diagram of ent-kaurene and ent-isokaurene, click here |
| Other name(s): |
OsKSL5i; OsKSL6 |
| Systematic name: |
ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-isokaurene-forming) |
| Comments: |
Two enzymes of the rice sub-species Oryza sativa ssp. indica, OsKSL5 and OsKSL6, produce ent-isokaurene. A variant of OsKSL5 from the sub-species Oryza sativa ssp. japonica produces ent-pimara-8(14),15-diene instead [cf. EC 4.2.3.30, ent-pimara-8(14),15-diene synthase]. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc |
| References: |
| 1. |
Xu, M., Wilderman, P.R., Morrone, D., Xu, J., Roy, A., Margis-Pinheiro, M., Upadhyaya, N.M., Coates, R.M. and Peters, R.J. Functional characterization of the rice kaurene synthase-like gene family. Phytochemistry 68 (2007) 312–326. [DOI] [PMID: 17141283] |
| 2. |
Xu, M., Wilderman, P.R. and Peters, R.J. Following evolution’s lead to a single residue switch for diterpene synthase product outcome. Proc. Natl. Acad. Sci. USA 104 (2007) 7397–7401. [DOI] [PMID: 17456599] |
|
| [EC 4.2.3.103 created 2012] |
| |
|
| |
|
Printable version