The Enzyme Database

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EC 4.2.3.181     
Accepted name: selina-4(15),7(11)-diene synthase
Reaction: (2E,6E)-farnesyl diphosphate = selina-4(15),7(11)-diene + diphosphate
For diagram of eudesmol and selinene biosynthesis, click here
Other name(s): SdS
Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, selina-4(15),7(11)-diene-forming)
Comments: Isolated from the bacteria Streptomyces pristinaespiralis and S. somaliensis.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
References:
1.  Rabe, P. and Dickschat, J.S. Rapid chemical characterization of bacterial terpene synthases. Angew. Chem. Int. Ed. Engl. 52 (2013) 1810–1812. [DOI] [PMID: 23307484]
2.  Baer, P., Rabe, P., Fischer, K., Citron, C.A., Klapschinski, T.A., Groll, M. and Dickschat, J.S. Induced-fit mechanism in class I terpene cyclases. Angew. Chem. Int. Ed. Engl. 53 (2014) 7652–7656. [DOI] [PMID: 24890698]
[EC 4.2.3.181 created 2017]
 
 


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