The Enzyme Database

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EC 4.2.3.207     
Accepted name: neoverrucosan-5β-ol synthase
Reaction: geranylgeranyl diphosphate + H2O = neoverrucosan-5β-ol + diphosphate
For diagram of related fungal and bacterial diterpenoids, click here
Glossary: neoverrucosan-5β-ol = (1aS,3R,3aS,5aR,8S,8aR,8bR,8cS)-1a,3a,5a-trimethyl-8-(propan-2-yl)tetradecahydrocyclopenta[a]cyclopropa[h]naphthalen-3-ol
Other name(s): SapTC1
Systematic name: geranylgeranyl- diphosphate diphosphate-lyase (neoverrucosan-5β-ol-forming)
Comments: Requires Mg2+. Characterized from the marine bacterium Saprospira grandis.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Yang, Y.L., Zhang, S., Ma, K., Xu, Y., Tao, Q., Chen, Y., Chen, J., Guo, S., Ren, J., Wang, W., Tao, Y., Yin, W.B. and Liu, H. Discovery and characterization of a new family of diterpene cyclases in bacteria and fungi. Angew. Chem. Int. Ed. Engl. 56 (2017) 4749–4752. [DOI] [PMID: 28371074]
[EC 4.2.3.207 created 2022]
 
 


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