EC |
4.2.3.208 |
Accepted name: |
verrucosan-2β-ol synthase |
Reaction: |
geranylgeranyl diphosphate + H2O = verrucosan-2β-ol + diphosphate |
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For diagram of related fungal and bacterial diterpenoids, click here |
Glossary: |
verrucosan-2β-ol = (1S,3aR,5aS,6aR,7aR,8S,8aR,9bR)-1-(propan=2-yl)tetradecahydrocyclopenta[a]cyclopropa[g]naphthalene-8-ol |
Other name(s): |
ChlTC2 |
Systematic name: |
geranylgeranyl-diphosphate diphosphate-lyase (verrucosan-2β-ol-forming) |
Comments: |
Requires Mg2+. Characterized from the bacterium Chloroflexus aurantiacus. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Yang, Y.L., Zhang, S., Ma, K., Xu, Y., Tao, Q., Chen, Y., Chen, J., Guo, S., Ren, J., Wang, W., Tao, Y., Yin, W.B. and Liu, H. Discovery and characterization of a new family of diterpene cyclases in bacteria and fungi. Angew. Chem. Int. Ed. Engl. 56 (2017) 4749–4752. [DOI] [PMID: 28371074] |
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[EC 4.2.3.208 created 2022] |
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