The Enzyme Database

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EC 4.2.3.210     
Accepted name: lydicene synthase
Reaction: geranylgeranyl diphosphate = lydicene + diphosphate
For diagram of related fungal and bacterial diterpenoids, click here
Glossary: lydicene = (4aR,6aS)-2,2,4α,6α,9-pentamethyl-1,3,4,5,6,7,10,11-octahydro-1H-cyclohepta[a]naphthalene
Other name(s): StlTC
Systematic name: geranylgerany-diphosphate diphosphate-lyase (lydicene-forming)
Comments: Requires Mg2+. Characterized from the bacterium Streptomyces lydicus.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Yang, Y.L., Zhang, S., Ma, K., Xu, Y., Tao, Q., Chen, Y., Chen, J., Guo, S., Ren, J., Wang, W., Tao, Y., Yin, W.B. and Liu, H. Discovery and characterization of a new family of diterpene cyclases in bacteria and fungi. Angew. Chem. Int. Ed. Engl. 56 (2017) 4749–4752. [DOI] [PMID: 28371074]
[EC 4.2.3.210 created 2022]
 
 


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