The Enzyme Database

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EC 4.2.3.219     
Accepted name: (2E)-α-cericerene synthase
Reaction: geranylfarnesyl diphosphate = (2E)-α-cericerene + diphosphate
For diagram of sesterterpenoids biosynthesis, click here
Glossary: (2E)-α-cericerene = (1E,4R,7E,11E)-1,7,11-trimethyl-4-[(2E)-6-methylhepta-2,5-dien-2-yl]cyclotetrdeca-1,7,11-triene
Other name(s): EvSS
Systematic name: geranylfarneyl-diphosphate diphosphate-lyase (cyclizing, (2E)-α-cericerene-forming)
Comments: A sesterterpenoid synthase enzyme isolated from the fungus Aspergillus stellatus.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Qin, B., Matsuda, Y., Mori, T., Okada, M., Quan, Z., Mitsuhashi, T., Wakimoto, T. and Abe, I. An unusual chimeric diterpene synthase from Emericella variecolor and its functional conversion into a sesterterpene synthase by domain swapping. Angew. Chem. Int. Ed. Engl. 55 (2016) 1658–1661. [DOI] [PMID: 26546087]
[EC 4.2.3.219 created 2023]
 
 


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