| EC |
4.2.3.229 |
| Accepted name: |
ent-beyerene synthase |
| Reaction: |
ent-copalyl diphosphate = ent-beyerene + diphosphate |
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For diagram of ent-atiserene, ent-kaurene and ent-isokaurene, click here |
| Glossary: |
ent-beyerene = ent-beyer-15-ene = beyer-15-ene |
| Other name(s): |
ent-kaurene synthase like 2; RcKSL4; OsKSL2; PpCPS/KS (ambiguous) |
| Systematic name: |
ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-beyerene-forming) |
| Comments: |
The enzyme has been shown to occur in castor bean (Ricinus communis) and rice (Oryza sativa). ent-Beyerene is also a product of EC 4.2.3.19 (ent-kaurene synthase) of the moss Physcomitrella patens. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Jackson, A.J., Hershey, D.M., Chesnut, T., Xu, M. and Peters, R.J. Biochemical characterization of the castor bean ent-kaurene synthase(-like) family supports quantum chemical view of diterpene cyclization. Phytochemistry 103 (2014) 13–21. [DOI] [PMID: 24810014] |
| 2. |
Tezuka, D., Ito, A., Mitsuhashi, W., Toyomasu, T. and Imai, R. The rice ent-kaurene synthase like 2 encodes a functional ent-beyerene synthase. Biochem. Biophys. Res. Commun. 460 (2015) 766–771. [DOI] [PMID: 25824047] |
| 3. |
Zhan, X., Bach, S.S., Hansen, N.L., Lunde, C. and Simonsen, H.T. Additional diterpenes from Physcomitrella patens synthesized by copalyl diphosphate/kaurene synthase (PpCPS/KS). Plant Physiol. Biochem. 96 (2015) 110–114. [DOI] [PMID: 26248039] |
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| [EC 4.2.3.229 created 2024] |
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