| EC |
4.2.3.230 |
| Accepted name: |
2-deoxy-4-epi-scyllo-inosose synthase |
| Reaction: |
D-mannose 6-phosphate = 2-deoxy-4-epi-scyllo-inosose + phosphate |
| Glossary: |
2-deoxy-4-epi-scyllo-inosose = (2R,3S,4S,5S)-2,3,4,5-tetrahydroxycyclohexan-1-one |
| Other name(s): |
eboD (gene name) |
| Systematic name: |
D-mannose-6-phosphate phosphate-lyase (2-deoxy-4-epi-scyllo-inosose-forming) |
| Comments: |
Requires Co2+ or Ni2+. The enzyme has been characterized from the cyanobacterium Nostoc punctiforme and the Gram-negative cellulose degrading bacterium Sporocytophaga myxococcoides. cf. EC 4.2.3.124, 2-deoxy-scyllo-inosose synthase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Tanoeyadi, S., Zhou, W., Osborn, A.R., Tsunoda, T., Samadi, A., Burade, S., Waldo, T.J., Higgins, M.A. and Mahmud, T. 2-Deoxy-4-epi-scyllo-inosose (DEI) is the product of EboD, a highly conserved dehydroquinate synthase-like enzyme in bacteria and eustigmatophyte algae. ACS Chem. Biol. 19 (2024) 2277–2283. [DOI] [PMID: 39404639] |
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| [EC 4.2.3.230 created 2025] |
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