| EC |
4.2.3.26 |
| Accepted name: |
R-linalool synthase |
| Reaction: |
geranyl diphosphate + H2O = (3R)-linalool + diphosphate |
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For diagram of acyclic monoterpenoid biosynthesis, click here |
| Glossary: |
(3R)-linalool = (3R)-3,7-dimethylocta-1,6-dien-3-ol |
| Other name(s): |
(3R)-linalool synthase; (–)-3R-linalool synthase |
| Systematic name: |
geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming] |
| Comments: |
Geranyl diphosphate cannot be replaced by isopentenyl diphosphate (3-methylbut-3-en-1-yl diphosphate), prenyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrate [1]. Requires Mg2+ or Mn2+ for activity. Unlike many other monoterpene synthases, only a single product, (3R)-linalool, is formed. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 254993-26-5 |
| References: |
| 1. |
Jia, J.W., Crock, J., Lu, S., Croteau, R. and Chen, X.Y. (3R)-Linalool synthase from Artemisia annua L.: cDNA isolation,
characterization, and wound induction. Arch. Biochem. Biophys. 372 (1999) 143–149. [DOI] [PMID: 10562427] |
| 2. |
Crowell, A.L., Williams, D.C., Davis, E.M., Wildung, M.R. and Croteau, R. Molecular cloning and characterization of a new linalool synthase. Arch. Biochem. Biophys. 405 (2002) 112–121. [DOI] [PMID: 12176064] |
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| [EC 4.2.3.26 created 2006] |
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