| EC |
4.2.3.41 |
| Accepted name: |
elisabethatriene synthase |
| Reaction: |
geranylgeranyl diphosphate = elisabethatriene + diphosphate |
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For diagram of diterpenoid biosynthesis, click here and for reaction mechanism, click here |
| Other name(s): |
elisabethatriene cyclase |
| Systematic name: |
geranylgeranyl-diphosphate diphosphate-lyase (elisabethatriene-forming) |
| Comments: |
Requires Mg2+ or less efficiently Mn2+. The enzyme is also able to use farnesyl diphosphate and geranyl diphosphate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 334022-59-2 |
| References: |
| 1. |
Kohl, A.C. and Kerr, R.G. Identification and characterization of the pseudopterosin diterpene cyclase, elisabethatriene synthase, from the marine gorgonian, Pseudopterogorgia elisabethae. Arch. Biochem. Biophys. 424 (2004) 97–104. [DOI] [PMID: 15019841] |
| 2. |
Bruck, T.B. and Kerr, R.G. Purification and kinetic properties of elisabethatriene synthase from the coral Pseudopterogorgia elisabethae. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 143 (2006) 269–278. [DOI] [PMID: 16423548] |
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| [EC 4.2.3.41 created 2009] |
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