EC |
4.2.3.55 |
Accepted name: |
(S)-β-bisabolene synthase |
Reaction: |
(2E,6E)-farnesyl diphosphate = (S)-β-bisabolene + diphosphate |
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For diagram of bisabolene biosynthesis, click here, for diagram of bisabolene biosynthesis, click here and for diagram of bisabolene and macrocarpene biosynthesis, click here |
Systematic name: |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(S)-β-bisabolene-forming] |
Comments: |
The synthesis of (S)-β-macrocarpene from (2E,6E)-farnesyl diphosphate proceeds in two steps. The first step is the cyclization to (S)-β-bisabolene. The second step is the isomerization to (S)-β-macrocarpene (cf. EC 5.5.1.17, (S)-β-macrocarpene synthase). The enzyme requires Mg2+ or Mn2+ for activity. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Fujisawa, M., Harada, H., Kenmoku, H., Mizutani, S. and Misawa, N. Cloning and characterization of a novel gene that encodes (S)-β-bisabolene synthase from ginger, Zingiber officinale. Planta 232 (2010) 121–130. [DOI] [PMID: 20229191] |
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[EC 4.2.3.55 created 2011] |
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