| EC |
4.2.3.95 |
| Accepted name: |
(-)-α-cuprenene synthase |
| Reaction: |
(2E,6E)-farnesyl diphosphate = (-)-α-cuprenene + diphosphate |
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For diagram of biosynthesis of bicyclic sesquiterpenoids derived from bisabolyl cation, click here and for diagram of trichodiene and (–)-α-cuprenene biosynthesis, click here |
| Other name(s): |
Cop6 |
| Systematic name: |
(-)-α-cuprenene hydrolase [cyclizing, (-)-α-cuprenene-forming] |
| Comments: |
The enzyme from the fungus Coprinopsis cinerea produces (-)-α-cuprenene with high selectivity. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Lopez-Gallego, F., Agger, S.A., Abate-Pella, D., Distefano, M.D. and Schmidt-Dannert, C. Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers. ChemBioChem 11 (2010) 1093–1106. [DOI] [PMID: 20419721] |
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| [EC 4.2.3.95 created 2012] |
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