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Your query returned 1 entry. 
Printable version
| EC | 4.3.1.13 | ||
| Accepted name: | carbamoyl-serine ammonia-lyase | ||
| Reaction: | O-carbamoyl-L-serine + H2O = pyruvate + 2 NH3 + CO2 (overall reaction) (1a) O-carbamoyl-L-serine = CO2 + NH3 + 2-aminoprop-2-enoate (1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous) (1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous) |
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| Other name(s): | O-carbamoyl-L-serine deaminase; carbamoylserine deaminase; O-carbamoyl-L-serine ammonia-lyase (pyruvate-forming) | ||
| Systematic name: | O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming) | ||
| Comments: | A pyridoxal-phosphate protein. The enzyme cleaves a carbon-oxygen bond, releasing CO2, ammonia, and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and a second ammonia molecule. The latter reaction, which can occur spontaneously, can also be catalysed by EC 3.5.99.10, 2-iminobutanoate/2-iminopropanoate deaminase. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 52227-64-2 | ||
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