|
Your query returned 1 entry. Printable version
EC | 4.3.1.25 | ||||||||
Accepted name: | phenylalanine/tyrosine ammonia-lyase | ||||||||
Reaction: | (1) L-phenylalanine = trans-cinnamate + NH3 (2) L-tyrosine = trans-p-hydroxycinnamate + NH3 |
||||||||
For diagram of chalcone and stilbene biosynthesis, click here | |||||||||
Other name(s): | PTAL; bifunctional PAL | ||||||||
Systematic name: | L-phenylalanine(or L-tyrosine):trans-cinnamate(or trans-p-hydroxycinnamate) ammonia-lyase | ||||||||
Comments: | This enzyme is a member of the aromatic amino acid lyase family, other members of which are EC 4.3.1.3 (histidine ammonia-lyase), EC 4.3.1.23 (tyrosine ammonia-lyase) and EC 4.3.1.24 (phenylalanine ammonia-lyase). The enzyme from some monocots, including maize, and from the yeast Rhodosporidium toruloides, deaminate L-phenylalanine and L-tyrosine with similar catalytic efficiency [3]. The enzyme contains the cofactor 3,5-dihydro-5-methylidene-4H-imidazol-4-one (MIO), which is common to this family [3]. This unique cofactor is formed autocatalytically by cyclization and dehydration of the three amino-acid residues alanine, serine and glycine [4]. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||
References: |
| ||||||||