EC |
4.3.1.31 |
Accepted name: |
L-tryptophan ammonia lyase |
Reaction: |
L-tryptophan = 3-indoleacrylate + NH3 |
Glossary: |
3-indoleacrylate = (2E)-3-(1H-indol-3-yl)prop-2-enoate |
Other name(s): |
WAL |
Systematic name: |
L-tryptophan ammonia-lyase (3-indoleacrylate-forming) |
Comments: |
The enzyme, characterized from the bacterium Rubrivivax benzoatilyticus JA2, requires no cofactors. It acts on L-phenylalanine and L-glutamate with about 60% of the activity with L-tryptophan, and on L-tyrosine, glycine, and L-alanine with about 30% of the activity. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Kumavath, R.N., Ramana ChV., Sasikala Ch, Barh, D., Kumar, A.P. and Azevedo, V. Isolation and characterization of L-tryptophan ammonia lyase from Rubrivivax benzoatilyticus strain JA2. Curr. Protein Pept. Sci. 16 (2015) 775–781. [DOI] [PMID: 25961404] |
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[EC 4.3.1.31 created 2016] |
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