| EC |
4.3.2.3 |
| Accepted name: |
ureidoglycolate lyase |
| Reaction: |
(S)-ureidoglycolate = glyoxylate + urea |
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For diagram of AMP catabolism, click here |
| Other name(s): |
ureidoglycolatase (ambiguous); ureidoglycolase (ambiguous); ureidoglycolate hydrolase (misleading); (S)-ureidoglycolate urea-lyase |
| Systematic name: |
(S)-ureidoglycolate urea-lyase (glyoxylate-forming) |
| Comments: |
This microbial enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 3.5.1.116, ureidoglycolate amidohydrolase, which releases ammonia rather than urea. |
| Links to other databases: |
BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9014-57-7 |
| References: |
| 1. |
Trijbels, F. and Vogels, G.D. Allantoate and ureidoglycolate degradation by Pseudomonas aeruginosa. Biochim. Biophys. Acta 132 (1967) 115–126. [DOI] [PMID: 6030341] |
| 2. |
Werner, A.K., Romeis, T. and Witte, C.P. Ureide catabolism in Arabidopsis thaliana and Escherichia coli. Nat. Chem. Biol. 6 (2010) 19–21. [DOI] [PMID: 19935661] |
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| [EC 4.3.2.3 created 1972, modified 2014] |
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