EC |
4.4.1.26 |
Accepted name: |
olivetolic acid cyclase |
Reaction: |
3,5,7-trioxododecanoyl-CoA = CoA + 2,4-dihydroxy-6-pentylbenzoate |
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For diagram of cannabinoid biosynthesis, click here |
Glossary: |
2,4-dihydroxy-6-pentylbenzoate = olivetolate |
Other name(s): |
OAC |
Systematic name: |
3,5,7-trioxododecanoyl-CoA CoA-lyase (2,4-dihydroxy-6-pentylbenzoate-forming) |
Comments: |
Part of the cannabinoids biosynthetic pathway in the plant Cannabis sativa. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
References: |
1. |
Gagne, S.J., Stout, J.M., Liu, E., Boubakir, Z., Clark, S.M. and Page, J.E. Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides. Proc. Natl. Acad. Sci. USA 109 (2012) 12811–12816. [DOI] [PMID: 22802619] |
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[EC 4.4.1.26 created 2012] |
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