| EC |
4.8.1.5 |
| Accepted name: |
thiohydroximate-O-sulfate sulfate/sulfur-lyase (nitrile-forming) |
| Reaction: |
an N-(sulfonatooxy)alkanimidothioate = a nitrile + sulfate + sulfur |
| Glossary: |
an N-(sulfonatooxy)alkanimidothioate = a thiohydroximate-O-sulfate |
| Other name(s): |
NSP (gene name); nitrile-specifier protein |
| Systematic name: |
thiohydroximate-O-sulfate sulfate/sulfur-lyase (nitrile-forming) |
| Comments: |
The enzyme is involved in the breakdown of glucosinolates. It can act on both aliphatic and aromatic glucosinolates, and forms nitrile-containing products. cf. EC 4.8.1.6, N-(sulfonatooxy)alkenimidothioic acid sulfate-lyase (epithionitrile-forming), and EC 4.8.1.7, phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Kissen, R. and Bones, A.M. Nitrile-specifier proteins involved in glucosinolate hydrolysis in Arabidopsis thaliana. J. Biol. Chem. 284 (2009) 12057–12070. [DOI] [PMID: 19224919] |
| 2. |
Burow, M., Losansky, A., Muller, R., Plock, A., Kliebenstein, D.J. and Wittstock, U. The genetic basis of constitutive and herbivore-induced ESP-independent nitrile formation in Arabidopsis. Plant Physiol. 149 (2009) 561–574. [DOI] [PMID: 18987211] |
|
| [EC 4.8.1.5 created 2022] |
| |
|
| |
|
Printable version