ExplorEnz: EC 5.1.3.10

Your query returned 1 entry. Printable version

5.1.3.10

Accepted name:

CDP-paratose 2-epimerase

Reaction:

CDP-α-D-paratose = CDP-α-D-tyvelose

For diagram of CDP-abequose, CDP-ascarylose, CDP-paratose and CDP-tyrelose biosynthesis, click here

Glossary:

CDP-α-D-tyvelose = CDP-3,6-dideoxy-α-D-mannose = CDP-3,6-dideoxy-α-D-arabino-hexose
CDP-α-D-paratose = CDP-3,6-dideoxy-α-D-glucose = CDP-3,6-dideoxy-α-D-ribo-hexose

Other name(s):

CDP-paratose epimerase; cytidine diphosphoabequose epimerase; cytidine diphosphodideoxyglucose epimerase; cytidine diphosphoparatose epimerase; cytidine diphosphate paratose-2-epimerase; CDP-abequose epimerase (incorrect); CDP-D-abequose 2-epimerase (incorrect); CDP-tyvelose 2-epimerase,

Systematic name:

CDP-3,6-dideoxy-D-glucose 2-epimerase

Comments:

Requires NAD⁺.

Links to other databases:

BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 37318-36-8

References:

1.	Matsuhashi, S. Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. II. Reversible 2-epimerization of cytidine diphosphate paratose. J. Biol. Chem. 241 (1966) 4275–4282. [PMID: 5924649]
2.	Liu, H.-W. and Thorson, J.S. Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria. Annu. Rev. Microbiol. 48 (1994) 223–256. [DOI] [PMID: 7826006]
3.	Koropatkin, N.M., Liu, H.W. and Holden, H.M. High resolution x-ray structure of tyvelose epimerase from Salmonella typhi. J. Biol. Chem. 278 (2003) 20874–20881. [DOI] [PMID: 12642575]

[EC 5.1.3.10 created 1972, modified 2005]